Title: Sleep Disorder Trends, Epigenetic Markers, and Genetic Variation of Circadian Genes in Adenomatous Polyp Formation
نویسنده
چکیده
Introduction: Sleep disturbances and sleep quality have allegedly increased and decreased over
منابع مشابه
ASD and Sleep Disorders
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by social communication deficits and repetitive behaviors/limited interests. There have been accumulated reports of significant sleep problems in ASD. The most common sleep problems include difficulties in sleep initiation and maintenance, irregular sleepawakening rhythm, and disordered sleep pattern. Some investigato...
متن کاملScreening of Clock Gene Polymorphisms Demonstrates Association of a PER3 Polymorphism with Morningness–Eveningness Preference and Circadian Rhythm Sleep Disorder
A system of self-sustained biological clocks controls the 24-h rhythms of behavioral and physiological processes such as the sleep-wake cycle. The circadian clock system is regulated by transcriptional and translational negative feedback loops of multiple clock genes. Polymorphisms in circadian clock genes have been associated with morningness-eveningness (diurnal) preference, familial advanced...
متن کاملEpigenetic events in the colorectum and in colon cancer.
Colon cancers arise from benign neoplasms and evolve into adenocarcinomas through a stepwise histological progression sequence, proceeding from either adenomas or hyperplastic polyps/serrated adenomas. Genetic alterations have been associated with specific steps in this polyp-adenocarcinoma sequence and are believed to drive the histological progression of colon cancer. Recently, epigenetic alt...
متن کاملActive BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile
BACKGROUND Sessile serrated polyps (SSPs) have emerged as important precursors for a large number of sporadic colorectal cancers. They are difficult to detect during colonoscopy due to their flat shape and the excessive amounts of secreted mucin that cover the polyps. The underlying genetic and epigenetic basis for the emergence of SSPs is largely unknown with existing genetic studies confined ...
متن کاملGenetic and Phenotypic Variation for Flowering Time Genes in Barley (Hordeum vulgare)
Objective: Flowering Time (FT) in cereals controlled by genes that had a main factor on plant development. Methods: Genetic and phenotypic diversity of four flowering time genes (FT2, FT3, FT4, Ppd-H1) in 19 genotypes of cultivated and wild barley was evaluated and a total of 107 alleles were amplified. Genotypes based on days to flowering time and molecular data were grouped into earl...
متن کامل